72518-14111

Institute of Pharmaceutical Research

Publications

  1. Shah, K., Shrivastava, S.K. and Mishra, P., (2013). Evaluation of mefenamic acid mutual prodrugs. Medicinal Chemistry Research, 22 (1), 70-77.
  2. Shah, K., Chhabra, S., Shrivastava, S.K. and Mishra, P., Benzimidazole: A promising pharmacophore. Medicinal Chemistry Research, Accepted
  3. Yadav, H.N.,Singh, M. and Sharma, P. L. (2012), Pharmacological inhibition of GSK-3β produces late phase of cardioprotection in hyperlipedemic rat heart: Possible involvement of HSP 72, Molecular and Cellular Biochemistry (369), 227-33. 
  4. Murti, Y.and Semwal, B.C. (2012) Pharmacovigilance in India: A Collaborative Approach, Journal of Pharmacovigilance & Drug Safety,9 (1), 01-06. 
  5. Murti, Y., Upadhyay, P.K., and Semwal, B.C., (2012) Early Detection of Autism: Ask the Expert,Pharma Buzz, 7(06), 12-18. 
  6. Uddin, K., Upadhyay, P.K., and Shakya, A.,(2012) Third Generation Anticonvulsants For The Treatment of Partial-Onset Seizures: An OverviewInternational Journal of Pharma World Research,3(3),1-13. 
  7. Upadhyay, P.K., Uddin, K., Sachan, K.,(2012) Benzimidazole-A Medicinally Important Heterocyclic Aromatic Organic Moiety: An OverviewInternational Journal of Pharma World Research,3(3), 1-10. 
  8. Gupta, J.K., Agrawal, K.K., Verma, A., Singh, K. (2012). Investigation of in-vitro anthelmintic activity of L. lavandulifoliaL. cephalotes and L. asperaJournal of Pharmacy Research, 5(1), 212-213. 
  9. Upmanyu, N.,  Kumar, S., Shah, K. and  Mishra, P.,  Synthesis and antimicrobial studies of some 4-(substituted)-ethanoylamino 3-mercapto-5-(4-substituted) phenyl-1,2,4-triazoles Dhaka Univ. J. Pharm. Sci. 11(1): 7-18, 2012. 
  10. Gupta, J.K., Agrawal, K.K., Verma, A., Singh, K. (2012). Investigation of in-vitro anthelmintic activity of L. lavandulifoliaL. cephalotes and L. aspera. Journal of pharmacy research, 5(1), 212-213. 
  11. Akhter, H., Gupta, J., Mohiuddin, M. and Shah, F. (2012). A comprehensive review on buccal drug delivery system, International journal of pharmaceutical research and development, 3(11), 59-77. 
  12. Gupta, J.K, Sharma, S.K., Misra, V., Patel, K. (2011). Evaluation of anti-nociceptive and anti-inflammatory activity of Punica granatum seed extract, International Research Journal of Pharmacy, 2(12), 235-237. 
  13. Upmanyu, N., Gupta, J.K., Shah, K., Mishra, P. (2011). Synthesis of New 1,2,4-Triazoles as anti-inflammatory and anti-nociceptive agents, Pharmaceutical Chemistry Journal, 45(7), 433-439. 
  14. Upmanyu, N., Gupta, J.K., Shah, K., Mishra, P. (2011). Anti inflammatory and anti-nociceptive evaluation of newly synthesized 4-(substituted ethanoyl) amino-3-mercapto-5-(4-methoxy) phenyl 1,2,4-Triazoles.Journal of Pharmacy and Bio allied Sciences, 3(2), 259-265. 
  15. Shrivastav, J., Shah, K., Mahadik, M. and Dhaneshwar, S.R., (2011) Application of HPTLC in the Simultaneous estimation of Thiocolchicoside and Diclofenac in bulk drug and pharmaceutical dosage form. Bulletin of Pharmaceutical Research, 1(3):34-37. 
  16. Upmanyu, N., Kumar,S., Kharya, M.D., Shah, K and Mishra, P. (2011) Synthesis and antimicrobial evaluation of some novel 1,2,4 – Triazole derivatives. Acta Poloniae Pharmaceutica - Drug Research, 68 (2). 213-221.\ 
  17. Gupta J. et. al., Nanoparticles formulation using counter-ion induced gelification technique: In-vitro Chloramphenicol Release. Int. J. Pharm. Pharm. Sci., 3 (3)2011, 66-70. 
  18. Upmanyu, N., Kumar, S., Porwal, P., Shah, K. and Mishra, P. (2011) Synthesis and evaluation of 4-(substituted)-acetylamino-3-mercapto-5-(4-substituted) phenyl-1,2,4-triazole derivatives as antimicrobial agents. Medicinal Chemistry Research, 19 (7).\ 
  19. Kumar, S., Joshi, A, Thakur, R.S., Pathak, A.K. and Shah, K. (2011) Simultaneous estimation of etoricoxib and thiocolchicoside by RP-HPLC method in combined dosage forms. Acta Poloniae Pharmaceutica - Drug  Research, 68 (6). 839-843. 
  20. Semwal, B.C., Agrawal K.K., Singh, K., Tandon S and Sharma S. (2011). Alopecia : Switch to herbal medicine, Journal of pharmaceutical research and opinion, 1(4), 101-104. 
  21. Tandon, S., Sharma, S., Rajput, R., Semwal, B., Yadav, P.K. and Singh, K. (2011). Biotech Drugs: The next boom in pharmaceutical market, Journal of pharmaceutical research and opinion 1(3), 76-79. 
  22. Sharma, S., Tandon, S., Semwal, B. and Singh, K (2011). Momordica charantia Linn.: A comprehensive review on better remedy. Journal of pharmaceutical research and opinion, 1(2), 42-47. 
  23. Sharma, S.,Jalapure, S.S., Semwal,B., Tandon, S. and Agarwal,N. (2011). Anthelminitic activity of the whole plant of Spharanthus indius Linn. International journal of ayurvedic and herbal medicine, 1 (1), 18-23. 
  24. Agarwal, T.K. and Murti, Y. (2011). Synthesis and bioevaluation of ketoconazole thiosemicarbazone analogues, International journal of pharmaceutical sciences and research, 2(12), 3156-3160. 
  25. Bahare, R.S., Gupta, J., Malik, S. and Sharma,N. (2011). New emerging targets for Type-2 Diabetes, International Journal of PharmTech Research, 3(2), 809-818. 
  26. Malik, S., Upadhyaya, P.K. and Miglani, S. (2011). Thiazolidinediones: A plethro of biological load, International Journal of PharmTech Research, 3(1), 62-75. 
  27. Agrawal, G.P., Shenoy, A., Ghosh, K and Prabhu, L. (2011). High performance liquid chromatographic analytical method for the determination of carboplatin in injections, Asian journal of chemistry, 23(10). 
  28. Venkataraman, S., Jain, S., Shah, K. and Upmanyu, N. (2010), Synthesis and Biological Activity of Some Novel Pyrazolines, Acta Poloniae Pharmaceutica , Drug Research, 67 (4). 361-366. 
  29. Gupta , J. K., Upmanyu,  N.,  Patnaik , A K ,  Mazumder , P.M. ( 2010).Evaluation of Anti-Ulcer Activity of Leucas lavandulifolia Sm.(Fam. Labiaatae) on Mucosal Lesion in Rats,  Asian Journal of  Pharmaceutical and Clinical Research, 3(2), 118-120. 
  30. Gupta,J.K, Rani,A., Mishra, P. and Mazumder, P.M.(2010).  Blood glucose lowering potential of stem bark of Berberis aristata DC in alloxan induced diabetic rats, Iranian Journal of Pharmacology and therapeutics9(1),134. 
  31. Gupta, J.K., Kumar, A., Chopra, M.P., Mishra, C. and Rani, Prabha.(2009). Anti-inflammatory activity of unriped fruit of Carissa carandas Linn.  Pharmbit International journal, 29(1), 74-77. 
  32. Gupta, J.K. and Kumar, A. (2009). Patients with disturbed biorhythm and secondary beneficial effect of melatonin. International Journal of Pharmacy and Pharmaceutical Sciences, 1(1), 47-50. 
  33. Gupta J. et. al., “Antihyperglycemic activity of root of Berberis aristata D.C. in alloxane induced diabetic rats”, July-Sept., 2009, 259-262. 
  34. Gupta, A., Mishra, P. and Shah, K. (2009) Simple UV spectrophotometric determination of Rosuvastatin calcium in pure form and in pharmaceutical formulations. E-Journal of Chemistry, 6 (1), 89-92. 
  35. Shah, K., Gupta, A. and Mishra, P. (2009) Extractive spectrophotometric methods for the determination of Etoricoxib in tablets. E-Journal of Chemistry, 6 (1) 207-212. 
  36. Mishra, P., Shah, K. and Gupta, A. (2009) Spectrophotometric methods for simultaneous estimation of Nebivolol Hydrochloride and Amlodipine Besylate in tablets ; International Journal of Pharmacy and Pharmaceutical Sciences, 1 (2), 55-61. 
  37. Gupta, J.K., Semwal, B.C., Shah, K. and Patnaik, A.K. (2008).Evaluation of antidiabetic and in vitro antioxidant activity of Leucas lavandulifolia Sm.  Indian Drugs, 45(9): 731-735. 
  38. Mishra, P., Gupta, A. and Shah, K. (2007) Spectrophotometric Determination of Ezetimibe in Pharmaceutical Formulation; Journal of the Indian chemical Society, 84, 945-947. 
  39. Mishra, P., Shah, K. and Gupta, A. (2007) UV and Extractive Spectrophotometric Methods for the Determination of Nebivolol Hydrochloride in Tablets, Journal of the Indian chemical Society, 84, 1242-1245. 
  40. Mishra, P., Gupta, A and Shah, K. (2007) Simultaneous Estimation of Atorvastatin Calcium and Amlodipine Besylate from Tablets,Indian Journal of Pharmaceutical Sciences, 69 (6), 831-833.

Ph D Projects

  • Evaluation of some synthetic Flavanones
  • Formulation design, optimization and evaluation of controlled release drug delivery systems by using microtechnology. 
  • Synthesis and pharmacological evaluation of some novel triazoles. 
  • Synthesis and biological evaluation of some new substituted 1,3,4-oxadiazoles, 1,3,4- thiadiazoles and 1,2,4- triazoles. 
  • Synthesis, formulation and evaluation of Non Steroidal Anti inflammatory agents. 
  • Development and evaluation of liquid dosage forms for poorly water soluble drugs using hydrotropic solubilisation technique. 
  • Possible involvement of erythropoietin in attenuation of remote renal preconditioning in hyperlipidemic rat heart.

Pharmaceutical Chemistry

  • Design, synthesis and biological evaluation of some new derivatives of 1-Acyl-2- Aryl- Pyrazolidine -3,5-di-one.
  • Design, synthesis and biological evaluation of some novel phenothiazines. 
  • Synthesis, and biological evaluation of some analogues of fluoroquinolones. 
  • Design, synthesis, characterization  and  biological  evaluation  of  Novel Pyrazoles and Isoxazoles 
  • Design, synthesis and biological evaluation of  some novel substituted 4-Thiazolidinones 
  • Design, synthesis and biological evaluation  of  novel substituted Benzimidazoles 
  • Synthesis of Flavanones as anticancer agents 
  • Development and validation of a stability indicating assay method on Indapamide by RP-HPLC in bulk and tablet dosage form 
  • Development and validation of a stability indicating assay method for griseofulvin by RP-HPLC in bulk and tablet dosage form 
  • Investigation on hepatoprotective activity of Calotropis procera (ait.) R. Br. Leaves 
  • Synthesis of modified natural flavonoids of biological interest. 
  • Chemical composition and pharmacological studies on Calotropis procera (Ait.) R. Br. leaves. 
  • Synthesis, Characterization and Biological Evaluation of some novel Pyrazoles 
  • Synthesis, Characterization and Biological Evaluation of some novel substituted Azetidinones 
  • Synthesis, Characterization and Biological Evaluation of some 2, 5-disubstituted -4-Thiazolidinone 
  • Development and Validation of a Stability Indicating Assay Method for Tolperisone by RP-HPLC and UV Spectroscopy in Bulk and Tablet Dosage form 
  • Development and Validation of a Stability Indicating Assay Method by HPLC and UV Spectroscopy for Estimation of Lafutidine
  • Spectrophotometric Determination of Metoprolol Tartrate andits Combination in Tablet 
  • Synthesis and Biological Evaluation of Substituted Benzimidazoles

Pharmacology

  • Possible involvement of Hemeoxygenase-1 in diabetes mellitus and hyperlipidemia induced vascular endothelial dysfunction.
  • Cardio protective effect of ischemic preconditioning in ovariectomized rat heart: Possible implication caveolin- eNOS platform. 
  • Modulation of streptozotocin and celecoxib induced experimental  dementia in Alzheimer disease in mice by carbachol. 
  • Implication of Ho-1 in streptozotocin induced diabetic nephropathy in rats. 
  • Antidiabetic activity of Citrullus lanatus  seeds on streptozotocin induced diabetic rats. 
  • Evaluation of anti-ulcer activity of  Ziziphus  mauritiana seeds and pulp in rats. 
  • Evaluation of effect of Sebania grandiflora seed extract on the amnesia induced celecoxib in mice. 
  • Possible involvement of opoid receptor like (ORL) receptor in remote aortic  preconditioning induced cardio protection in rat heart. 
  • Pharmacological activity of Plumbago zeylanica  for its anti-hemorrhoidal  activity. 
  • Possible involvement of adenosine receptor and HO-1 in attenuated cardioprotective effect of ischemic preconditioning in hyperlipidemic rat heart. 
  • Evaluation of anti-ulcer activity of Manilkara zapota leaves extarct in albino rats. 
  • Possible implication of endogenous cannabinoid and transient  receptor potential vanalloid receptor-1 in chronic alcoholism induced neuropathic pain in wistar rat. 
  • Evaluation of anti-ulcer activity of  Anthocephalus cadamba bark extract in albino rats. 
  • Effect of  reseveratrol in 3-NP induced Huntington’s disease in rat : possible involvement of gsk-3β. 
  • Synthesis and pharmacological evaluation of 13,4-oxadiazole. 
  • Antidiabetic activity of Delonix regia  flower extract on streptozotocin induced diabetic rats. 
  • Effect of erythropoietin post conditioning  in isolated  hyperlipidemic rat heart: Possible implication of PI3K signaling pathway. 
  • Evaluation of anti-ulcer activity of  Clitorea ternatea leaves extract in albino rats 
  • Gastro protective potential of Hibiscus rosa-sinensis on mucosal lesion on rats. 
  • Comparative antidiabetic activity of Cassia fistula and Terminalia arjuna
  • Antidiabetic activity of Alocasia macrorriza on alloxan induced rats. 
  • Antiulcer activity of Calotropis procera seeds in experimentally induced ulcer in albino rats. 
  • Pharmacological investigation of Ponica granatum fruit extracts. 
  • Antidiabetic activity on the leaves of Calotropis procera and Calotropis gigentian in STZ induced rats. 
  • Hepatorotective activity of leaves of Spinacia oleracae. 
  • Antimutagenic activity of fruits of Anethum graveolens and Carum carvi. 
  • Pharmacological and toxicological evaluation of Clitoria ternatea
  • Determination of the anti-ulcer activity of the Plumeria rubra leaves extract. 
  • Comparative antiulcer activity of pulp and seeds extract ofCucumis melon
  • Antidiarrhoeal activity of Echinops echinatus on albino rats. 
  • Antiulcer activity of Anthocephalus cadamba on albuno rats. 
  • Memory enhancer activity of the bark of Saraca ashoka
  • Antidepressant activity of Elettaria cardamomum. 
  • Antiulcer activity of Aegle marmelos leaves and pulp. 
  • Antiulcer activity of Beta vulgaris roots.
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